
ELK Biotechnology NIPP1 rabbit pAb
인간 PPP1R8 유래 펩타이드로 면역화된 NIPP1 rabbit polyclonal antibody. WB 및 ELISA에 적합하며, 핵 및 세포질에서 발현되는 NIPP1 단백질 검출에 사용. 고순도 IgG, 1 mg/ml 농도, -20°C에서 1년 보관 가능.
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제품명
NIPP1 rabbit pAb
공급업체
ELK Biotechnology
제품 개요
NIPP1 rabbit polyclonal antibody는 인간 PPP1R8 유래 합성 펩타이드(AA 196-245)를 면역원으로 제작된 항체입니다. 이 항체는 NIPP1 단백질을 인식하며, WB 및 ELISA 분석에 적합합니다.
스펙 정보
| 항목 | 내용 |
|---|---|
| Alternative Names | PPP1R8; ARD1; NIPP1; Nuclear inhibitor of protein phosphatase 1; NIPP-1; Protein phosphatase 1 regulatory inhibitor subunit 8 |
| Applications | WB; ELISA |
| Recommended Dilutions | Western Blot: 1/500 - 1/2000 ELISA: 1/20000 Not yet tested in other applications |
| Immunogen | Synthesized peptide derived from human PPP1R8 (AA range: 196-245) |
| Host | Rabbit |
| Storage | -20°C / 1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band | 40 kD |
| GeneID (Human) | 5511 |
| Human Swiss-Prot No | Q12972 |
| Cellular Localization | Nucleus, Nucleus speckle. Primarily nuclear. [Isoform Gamma]: Cytoplasm, mainly cytoplasmic. |
| Species Reactivity | Human; Mouse; Rat |
Background
This gene, through alternative splicing, encodes three different isoforms. Two of the protein isoforms encoded by this gene are specific inhibitors of type 1 serine/threonine protein phosphatases and can bind but not cleave RNA. The third protein isoform lacks the phosphatase inhibitory function but acts as a single-strand endoribonuclease comparable to RNase E of E. coli. This isoform requires magnesium for its function and cleaves specific sites in A+U-rich regions of RNA.
[provided by RefSeq, Jul 2008]
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