ELK Biotechnology PTG rabbit pAb
Human 및 Monkey에서 반응하는 PTG rabbit polyclonal antibody로, PPP1R3C 단백질을 인식합니다. WB, IHC, IF, ELISA 등 다양한 응용에 적합하며, 고순도 IgG 형태로 제공됩니다. -20°C에서 1년간 안정적으로 보관 가능합니다.
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제품명
PTG rabbit pAb
공급업체
ELK Biotechnology
제품 개요
이 항체는 인간 PPP1R3C 단백질을 기반으로 제작된 rabbit polyclonal antibody입니다. Protein phosphatase 1 (PP1) 복합체의 조절 서브유닛으로 작용하며, glycogen 대사 조절에 중요한 역할을 하는 단백질을 인식합니다.
제품 스펙
| 항목 | 내용 |
|---|---|
| Alternative Names | PPP1R3C; PPP1R5; Protein phosphatase 1 regulatory subunit 3C; Protein phosphatase 1 regulatory subunit 5; PP1 subunit R5; Protein targeting to glycogen; PTG |
| Applications | WB; IHC; IF; ELISA |
| Recommended Dilutions | WB: 1/500–1/2000 IHC: 1/100–1/300 ELISA: 1/20000 Other applications: Not yet tested |
| Immunogen | Synthesized peptide derived from human PPP1R3C (AA range: 44–93) |
| Host | Rabbit |
| Storage | -20°C, 1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band | 36 kD |
| GeneID (Human) | 5507 |
| Human Swiss-Prot No | Q9UQK1 |
| Cellular Localization | Cytosol |
| Species Reactivity | Human; Monkey |
Background
This gene encodes a carbohydrate-binding protein that is a subunit of the protein phosphatase 1 (PP1) complex. PP1 catalyzes reversible protein phosphorylation, which is important in a wide range of cellular activities. The encoded protein affects glycogen biosynthesis by activating glycogen synthase and limiting glycogen breakdown by reducing glycogen phosphorylase activity. DNA hypermethylation of this gene has been found in colorectal cancer patients. The encoded protein also interacts with the laforin protein, which is implicated in Lafora disease.
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