ELK Biotechnology FEV rabbit pAb
FEV 단백질을 인식하는 토끼 폴리클로날 항체로, 인간·쥐·생쥐 시료에 반응합니다. WB 및 ELISA에 적합하며, 고순도의 IgG 형태로 제공됩니다. N-말단 합성 펩타이드로부터 유래된 면역원 사용. 핵 내 발현 단백질 검출에 유용합니다.
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FEV rabbit pAb
제품 정보
| 항목 | 내용 |
|---|---|
| Product name | FEV rabbit pAb |
| Alternative Names | FEV; PET1; Protein FEV; Fifth Ewing variant protein; PC12 ETS domain-containing transcription factor 1; PC12 ETS factor 1; Pet-1 |
| Applications | WB; ELISA |
| Recommended Dilutions | Western Blot: 1/500 - 1/2000 ELISA: 1/40000 Not yet tested in other applications. |
| Immunogen | Synthesized peptide derived from the N-terminal region of human FEV. |
| Host | Rabbit |
| Storage | -20°C / 1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band | 25 kD |
| GeneID (Human) | 54738 |
| Human Swiss-Prot No. | Q99581 |
| Cellular Localization | Nucleus |
| Species Reactivity | Human; Rat; Mouse |
Background
This gene belongs to the ETS transcription factor family. ETS family members have a highly conserved 85-amino acid ETS domain that binds purine-rich DNA sequences. The alanine-rich C-terminus of this gene indicates that it may act as a transcription repressor.
This gene is exclusively expressed in neurons of the central serotonin (5-HT) system, a system implicated in the pathogeny of psychiatric diseases such as depression, anxiety, and eating disorders.
In some types of Ewing tumors, this gene is fused to the Ewing sarcoma (EWS) gene following chromosome translocations.
[provided by RefSeq, Jul 2008]
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