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ELK Biotechnology SNAT2 rabbit pAb
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SNAT2(SLC38A2) 단백질을 인식하는 토끼 폴리클로날 항체로, WB, ELISA, IHC에 사용 가능. 인간, 생쥐, 랫트 반응성. 세포막 단백질 검출에 적합하며, 고순도 IgG(1 mg/ml)로 제공. -20°C에서 1년 보관 가능.
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ELK Biotechnology ES6652-100UL SNAT2 rabbit pAb, 100UL pk판매 단위 pk ·
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402,000원VAT 포함 442,200원
ELK Biotechnology ES6652-50UL SNAT2 rabbit pAb, 50UL pk판매 단위 pk ·
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301,000원VAT 포함 331,100원
ELK Biotechnology · ELK Biotechnology SNAT2 rabbit pAb
제품명
SNAT2 rabbit pAb
제품 정보
| 항목 | 내용 |
|---|---|
| Product name | SNAT2 rabbit pAb |
| Alternative Names | SLC38A2; ATA2; KIAA1382; SAT2; SNAT2; Sodium-coupled neutral amino acid transporter 2; Amino acid transporter A2; Protein 40-9-1; Solute carrier family 38 member 2; System A amino acid transporter 2; System A transporter 1; System N amino acid transporter |
| Applications | WB; ELISA; IHC |
| Recommended Dilutions | WB 1:500–2000; IHC-p 1:50–300; ELISA 1:2000–20000 |
| Immunogen | Synthesized peptide derived from human SLC38A2 (AA range: 151–200) |
| Host | Rabbit |
| Storage | -20°C / 1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band | 50 kDa |
| Gene ID (Human) | 54407 |
| Human Swiss-Prot No. | Q96QD8 |
| Species Reactivity | Human; Rat; Mouse |
| Cellular Localization | Cell membrane; Multi-pass membrane protein. Insulin promotes recruitment to the plasma membrane from a pool localized in the trans-Golgi network or endosomes. Enriched in the somatodendritic compartment of neurons, also detected at the axonal shaft but excluded from the nerve terminal. |
Background
- Function: Sodium-dependent amino acid transporter mediating pH-sensitive, electrogenic cotransport of neutral amino acids and sodium ions (1:1 stoichiometry).
- Regulation: Inhibited by N-methyl-D-glucamine and probably choline.
- Expression: Ubiquitously expressed, with high levels in the central nervous system, especially in caudal regions. Expressed by glutamatergic and GABAergic neurons, astrocytes, and other non-neuronal cells in the cerebral cortex.
- Induction: Up-regulated under hypertonic conditions and amino acid deprivation.
- Post-translational Modification: Polyubiquitination by NEDD4L regulates degradation and activity.
- Miscellaneous: Depletion of SLC38A2 by siRNA prevents recovery from hypertonic stress.
- Similarity: Belongs to the amino acid/polyamine transporter 2 family.
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