ELK Biotechnology PMS2/PMS2CL rabbit pAb
PMS2/PMS2CL 단백질을 인식하는 토끼 폴리클로날 항체로, IHC, IF, ELISA에 사용 가능. 휴먼, 랫, 마우스 반응성. 합성 펩타이드(AA 125-174)로부터 면역화. -20°C에서 1년 보관 가능.
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PMS2/PMS2CL rabbit pAb
제품 개요
ELK Biotechnology의 PMS2/PMS2CL rabbit pAb는 DNA mismatch repair 관련 단백질인 PMS2/PMS2CL을 인식하는 토끼 폴리클로날 항체입니다. IHC, IF, ELISA 등 다양한 면역분석에 사용할 수 있습니다.
제품 정보
| 항목 | 내용 |
|---|---|
| Product name | PMS2/PMS2CL rabbit pAb |
| Alternative Names | PMS2CL; Protein PMS2CL; PMS2-C terminal-like protein; PMS2; PMSL2; Mismatch repair endonuclease PMS2; DNA mismatch repair protein PMS2; PMS1 protein homolog 2 |
| Applications | IHC; IF; ELISA |
| Recommended Dilutions | IHC: 1/100–1/300 ELISA: 1/5000 Not yet tested in other applications |
| Immunogen | Synthesized peptide derived from human PMS2CL (AA range: 125–174) |
| Host | Rabbit |
| Storage | -20°C, 1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Gene ID (Human) | 5395 |
| Human Swiss-Prot No. | Q68D20 / P54278 |
| Cellular Localization | Mismatch repair complex |
| Species Reactivity | Human; Rat; Mouse |
Background
Caution: According to PubMed:15077197, PMS2CL is a pseudogene. However, a peptide specific to this protein was identified by mass spectrometry (PubMed:17525332). The discrepancy may be due to transcript frame differences, explaining why PubMed:15256438 could not detect this protein on Western blot.
PTM: Phosphorylated upon DNA damage, probably by ATM or ATR.
Sequence caution: Possible wrong choice of transcript.
Similarity: Belongs to the DNA mismatch repair mutL/hexB family.
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