ELK Biotechnology EDG-8 rabbit pAb

제품명

EDG-8 rabbit pAb

제품 개요

EDG-8(S1PR5)은 sphingosine 1-phosphate(S1P) 수용체로, 세포 증식, 이동, 신경 돌기 수축 등 다양한 세포 반응 조절에 관여합니다. 본 항체는 인간 EDG8 유래 합성 펩타이드(AA 335-384)에 대해 제작된 토끼 폴리클로날 항체입니다.

제품 정보

Background

The lysosphingolipid sphingosine 1-phosphate (S1P) regulates cell proliferation, apoptosis, motility, and neurite retraction. Its actions may occur both intracellularly as a second messenger and extracellularly as a receptor ligand. S1P and the structurally related lysolipid mediator lysophosphatidic acid (LPA) signal cells through G protein-coupled receptors known as EDG receptors. Some EDG receptors (e.g., EDG1; MIM 601974) are S1P receptors, while others (e.g., EDG2; MIM 602282) are LPA receptors. [Supplied by OMIM, Mar 2008]