ELK Biotechnology N-Shc rabbit pAb
N-Shc rabbit pAb는 인간 SHC3 유래 펩타이드로 제작된 폴리클로날 항체로, 신경세포 신호전달 연구에 적합합니다. IHC, IF, ELISA에 사용 가능하며, 뇌 조직 특이적 단백질 분석에 유용합니다. -20°C에서 1년 보관 가능합니다.
- 판매단위
- pk
카탈로그
2개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다ELK Biotechnology · ELK Biotechnology N-Shc rabbit pAb
ELK Biotechnology N-Shc rabbit pAb
제품 정보
| 항목 | 내용 |
|---|---|
| Product Name | N-Shc rabbit pAb |
| Alternative Names | SHC3; NSHC; SHCC; SHC-transforming protein 3; Neuronal Shc; N-Shc; Protein Rai; SHC-transforming protein C; Src homology 2 domain-containing-transforming protein C3; SH2 domain protein C3 |
| Applications | IHC; IF; ELISA |
| Recommended Dilutions | Immunohistochemistry: 1/100 - 1/300 ELISA: 1/10000 Not yet tested in other applications |
| Immunogen | The antiserum was produced against synthesized peptide derived from human SHC3 (AA range: 291–340) |
| Host | Rabbit |
| Storage | -20°C / 1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band | 48 kD |
| Gene ID (Human) | 53358 |
| Human Swiss-Prot No. | Q92529 |
| Cellular Localization | Cytosol, plasma membrane |
| Species Reactivity | Human; Mouse; Rat |
Background
Signaling adapter that couples activated growth factor receptors to signaling pathways in neurons. Involved in the signal transduction of neurotrophin-activated Trk receptors in cortical neurons.
PTM: Tyrosine phosphorylated.
Similarity: Contains 1 PID domain and 1 SH2 domain.
Subunit: Interacts with Trk receptors in a phosphotyrosine-dependent manner; once activated, binds to GRB2. Also interacts with activated EGF receptors.
Tissue Specificity: Mainly expressed in the brain. Hardly detectable in other tissues except the pancreas. Highly expressed in the cerebral cortex, frontal and temporal lobes, occipital pole, hippocampus, caudate nucleus, and amygdala. Expressed at low levels in the cerebellum, medulla, and spinal cord.
ELK Biotechnology 상품 둘러보기
전체보기
문의
0개 · 배송·재고 문의는 실시간 상담이 빠릅니다아직 등록된 문의가 없어요.