ELK Biotechnology Laminin α-5 rabbit pAb
Laminin α-5 단백질을 인식하는 토끼 폴리클로날 항체로, WB, IHC, IF, ELISA에 사용 가능. 인간 및 생쥐 시료 반응성. 세포외 기질 및 basement membrane 연구에 적합. 고순도 IgG, 1 mg/ml 농도, -20°C 보관.
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제품명
Laminin α-5 rabbit pAb
주요 정보
| 항목 | 내용 |
|---|---|
| Alternative Names | LAMA5; KIAA0533; KIAA1907; Laminin subunit alpha-5; Laminin-10 subunit alpha; Laminin-11 subunit alpha; Laminin-15 subunit alpha |
| Applications | WB; IHC; IF; ELISA |
| Recommended Dilutions | Western Blot: 1/500 - 1/2000 IHC-p: 1/100 - 1/300 ELISA: 1/20000 IF: 1/100 - 1/300 Not yet tested in other applications |
| Immunogen | The antiserum was produced against synthesized peptide derived from human LAMA5 (AA range: 2381–2430) |
| Host | Rabbit |
| Storage | -20°C / 1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band | 400 kD |
| GeneID (Human) | 3911 |
| Human Swiss-Prot No | O15230 |
| Cellular Localization | Secreted, extracellular space, extracellular matrix, basement membrane. Major component. |
| Species Reactivity | Human; Mouse |
Background
This gene encodes one of the vertebrate laminin alpha chains. Laminins, a family of extracellular matrix glycoproteins, are the major noncollagenous constituent of basement membranes. They are involved in diverse biological processes including cell adhesion, differentiation, migration, signaling, neurite outgrowth, and metastasis. Laminins consist of three non-identical chains—alpha, beta, and gamma—and form a cruciform structure. The protein encoded by this gene is the alpha-5 subunit of laminin-10 (laminin-511), laminin-11 (laminin-521), and laminin-15 (laminin-523).
[provided by RefSeq, Jun 2013]
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