Thermo Fisher Scientific PKC beta Polyclonal Antibody
PKC beta 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot, IHC, ICC/IF 등 다양한 응용에 적합. 항원 친화 크로마토그래피로 정제된 고품질 항체. 인간, 생쥐, 랫 등 다종 반응성 보유. 연구용으로만 사용 가능.
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- pk
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:3,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100–1:1,000 |
| Immunocytochemistry (ICC/IF) | 1:100–1:1,000 |
| Functional Assay | Assay-dependent |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat, Xenopus |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fragment corresponding to a region within amino acids 70–284 of Human PKC beta |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.48 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS (pH 7) with 1% BSA, 20% glycerol |
| Contains | 0.025% ProClin 300 |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2547155 |
Product Specific Information
- Recommended positive controls: SK-N-SH, IMR32, SK-N-AS
- Predicted reactivity: Mouse (98%), Rat (98%), Rabbit (98%), Rhesus Monkey (100%), Bovine (97%)
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases activated by calcium and diacylglycerol. PKC family members phosphorylate diverse protein targets and are involved in various cellular signaling pathways. They act as major receptors for phorbol esters, a class of tumor promoters. Each PKC family member has a specific expression profile and distinct cellular roles. PKC beta is implicated in B cell activation, apoptosis induction, endothelial proliferation, and intestinal sugar absorption. Mouse studies suggest roles in neuronal regulation and stress-related behaviors. Alternatively spliced transcript variants encoding distinct isoforms have been reported.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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