Thermo Fisher Scientific RACGAP1 Polyclonal Antibody
RACGAP1 단백질을 표적하는 Thermo Fisher Scientific의 염소 유래 폴리클로날 항체입니다. Western blot, IHC, ICC/IF, Flow cytometry 등 다양한 응용에 사용 가능하며, 인간에 반응합니다. 액상 형태로 제공되며 0.5 mg/mL 농도, TBS 버퍼에 BSA 및 sodium azide 포함.
- 카탈로그번호
- PA518005
- 판매단위
- pk
카탈로그
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.3–1 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1 µg/mL |
| Immunocytochemistry (ICC/IF) | 10 µg/mL |
| Flow Cytometry (Flow) | 10 µg/mL |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide sequence (GRQGNFFASPMLK) corresponding to the C-terminus amino acids of RACGAP1 (aa 620–632) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Ammonium sulfate precipitation |
| Storage Buffer | TBS, pH 7.3, with 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | –20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_10983166 |
Product Specific Information
- Predicted to react with bovine and canine based on sequence homology.
- Tested in Peptide ELISA: antibody detection limit dilution 32,000.
Target Information
RAC, a small GTPase in the ras family, regulates the formation of membrane ruffles, lamellipodia, and filopodia. It is involved in cytoskeletal actin organization and transformation. The p21 activated kinases (PAKs) are direct targets of active Rac and Cdc42, which can induce the assembly of polarized cytoskeletal structures when expressed in fibroblasts. RAC1 and RAC2 are also essential components of NADPH oxidase, the enzyme responsible for generating free radicals.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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