Thermo Fisher Scientific RRAS Polyclonal Antibody
RRAS 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody로, Human, Mouse, Rat 시료에서 사용 가능. Western Blot에 적합하며, 고순도 Affinity chromatography 정제. PBS 및 50% glycerol 저장 buffer 포함, -20°C 보관.
- 카탈로그번호
- PA5106240
- 판매단위
- pk
카탈로그
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Thermo Fisher Scientific RRAS Polyclonal Antibody
Applications
- Western Blot (WB)
Tested Dilution: 1:500–1:2,000
Species Reactivity
- Human
- Mouse
- Rat
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human RRAS (Accession P10301), corresponding to amino acid residues G39–E89 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2853932 |
Product Specific Information
Antibody detects endogenous levels of total R-Ras.
Target Information
The Ras superfamily of small GTPases includes the Ras, Rho, Arf, Rab, and Ran families. Ras-regulated signaling pathways control actin cytoskeletal integrity, proliferation, differentiation, cell adhesion, apoptosis, and cell migration. These GTPases function as molecular switches that control eukaryotic cell function by cycling between a GDP-bound inactive form and a GTP-bound active form.
Ras proteins are attached to the cell membrane by prenylation. Mutations in Ras family proto-oncogenes (H-Ras, N-Ras, K-Ras) are common, found in 20–30% of all human tumors. K-Ras mutations occur frequently in non-small-cell lung, colorectal, and pancreatic carcinomas; H-Ras mutations are common in bladder, kidney, and thyroid carcinomas; N-Ras mutations are found in melanoma, hepatocellular carcinoma, and hematologic malignancies.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(이미지: PA5-106240_RRAS_P10301-1_Rabbit.svg, PA5-106240_RRAS_P10301-1_Rabbit_PDP.jpeg)
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