Thermo Fisher Scientific Collagen VII Polyclonal Antibody
Thermo Fisher Scientific의 Collagen VII Polyclonal Antibody는 Mouse 및 Rat에 반응하며, Western Blot과 IHC(Paraffin)에 적합합니다. 합성 펩타이드 면역원으로 제작된 Rabbit Polyclonal 항체로, Collagen alpha-1(VII) chain에 특이적입니다. 연구용으로만 사용됩니다.
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Applications
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:100–1:2,000 | - |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:1,000 | - |
| Miscellaneous PubMed (Misc) | - | View 1 publication |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Mouse, Rat |
| Published Species | Not Applicable |
| Host / Isotype | Rabbit / Ig |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide from aa region 750–800 of rat collagen VII conjugated to blue carrier protein |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | Not Determined |
| Storage Buffer | Whole serum |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Glycerol (1:1) may be added for added stability. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Reconstitute in 100 µL of sterile water. Centrifuge to remove any insoluble material.
- The peptide is homologous with mouse sequence.
- Specificity: Collagen alpha-1(VII) chain.
Target Information
This gene encodes the alpha chain of type VII collagen. The type VII collagen fibril, composed of three identical alpha collagen chains, is restricted to the basement zone beneath stratified squamous epithelia. It functions as an anchoring fibril between the external epithelia and the underlying stroma.
Mutations in this gene are associated with all forms of dystrophic epidermolysis bullosa.
In the absence of mutations, an acquired form of this disease can result from an autoimmune response made to type VII collagen.
[provided by RefSeq, Jul 2008]
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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