Thermo Fisher Scientific FH/Fumarate Hydratase Polyclonal Antibody
Thermo Fisher Scientific의 FH/Fumarate Hydratase Polyclonal Antibody는 Western blot과 Immunoprecipitation에 적합한 토끼 유래 다클론 항체입니다. 인간 FH 단백질의 150~200번 잔기 영역을 면역원으로 사용하며, 액상 형태로 제공되고 4°C에서 보관합니다. 연구용으로만 사용 가능합니다.
- 카탈로그번호
- A305262Ax (2개 옵션)
- 판매단위
- pk
카탈로그
2개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific FH/Fumarate Hydratase Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000–1:10,000 |
| Immunoprecipitation (IP) | 2–10 µg/mg lysate |
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 150 to 200 of human Fumarate hydratase, mitochondrial |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
- Recommended shelf life: 1 year from date of receipt
- Based on 100% sequence identity, this antibody is predicted to react with Rat and Pig
Target Information
The protein encoded by this gene is an enzymatic component of the tricarboxylic acid (Krebs) cycle and catalyzes the formation of L-malate from fumarate. It exists in both cytosolic and mitochondrial forms, differing by the translation start site. The mitochondrial form undergoes N-terminal processing to yield the same mature form as in the cytoplasm. The enzyme functions as a homotetramer and shares similarity with thermostable class II fumarases. Mutations in this gene can result in fumarase deficiency, leading to progressive encephalopathy.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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