Thermo Fisher Scientific EPB41L4B Polyclonal Antibody
Thermo Fisher Scientific의 EPB41L4B Polyclonal Antibody는 인간 단백질을 인식하는 염소 유래 IgG 항체로, WB 및 IHC(P) 적용 가능. 비결합형 액상 형태이며, 고순도 암모늄 황산염 침전으로 정제됨. 세포 부착 및 이동 관련 연구에 적합.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.3 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 3.75 µg/mL |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Peptide with sequence C-HNYQPQYHPNIHPSQ |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Ammonium sulfate precipitation |
| Storage Buffer | TBS, pH 7.3, with 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2932960 |
Product Specific Information
This antibody is expected to recognise both reported isoforms (NP_060894.2; NP_061987.3).
Tested in Peptide ELISA: antibody detection limit dilution 1:64,000.
Target Information
Up-regulates the activity of the Rho guanine nucleotide exchange factor ARHGEF18. Involved in regulation of the circumferential actomyosin belt in epithelial cells (PubMed:22006950). Promotes cellular adhesion, migration, and motility in vitro and may play a role in wound healing (PubMed:23664528). May have a role in mediating cytoskeletal changes associated with steroid-induced cell differentiation (PubMed:14521927). [UniProt]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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