Thermo Fisher Scientific AID Monoclonal Antibody (EK2-5G9)

Applications

Tested Dilution

Publications

Western Blot (WB)

Assay-dependent

-

Immunohistochemistry (Paraffin) (IHC (P))

Assay-dependent

-

Flow Cytometry (Flow)

Assay-dependent

-

ELISA (ELISA)

Assay-dependent

-

Product Specifications

Host/Isotype

Rat / IgG2b

Class

Monoclonal

Type

Antibody

Clone

EK2-5G9

Immunogen

Synthetic peptide corresponding to amino acids 185-198 of human AID. if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:AID,uniProtId:Q9GZX7-1,ncbiNodeId:9606,antigenRange:185-198,antigenLength:198,antigenImageFileName:MA5-16665_AID_Q9GZX7-1_Rat.svg,antigenImageFileNamePDP:MA5-16665_AID_Q9GZX7-1_Rat_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2538159

Product Specific Information

Membrane permeabilization is required for flow cytometry applications. For FACS analysis, use 10 µL of the suggested working dilution to label 1x10^6 cells in 100 µL. A suggested positive control for immunohistochemical applications is Germinal centre b cells.

Rat anti Human AID antibody, clone EK2-5G9 recognizes human Single-stranded DNA cytosine deaminase, also known as Activation-induced cytidine deaminase or Cytidine aminohydrolase.

Target Information

This gene encodes a RNA-editing deaminase that is a member of the cytidine deaminase family. The protein is involved in somatic hypermutation, gene conversion, and class-switch recombination of immunoglobulin genes. Defects in this gene are the cause of autosomal recessive hyper-IgM immunodeficiency syndrome type 2 (HIGM2).

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.