Thermo Fisher Scientific DNAJB2 Monoclonal Antibody (OTI4D12), TrueMAB

Applications

Product Specifications

Product Specific Information

For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments using this carrier-free antibody, perform additional desalting (e.g., Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).

Target Information

The DnaJ family is one of the largest chaperone families, characterized by the J domain. DnaJ heat shock proteins from E. coli are regulated by the htpR protein and play key roles in the HSP70 chaperone system by stimulating ATP hydrolysis. These proteins contain cysteine-rich zinc finger regions forming peptide-binding domains essential for chaperone function.
DnaJ proteins mediate proteolysis and regulate protein degradation, exocytosis, and endocytosis.
DnaJB2 (DnaJ homolog subfamily B member 2), also known as HSJ1 or HSPF3, is primarily expressed in the brain, especially in the frontal cortex and hippocampus. Two isoforms are generated by alternative splicing.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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