Thermo Fisher Scientific KV1.2 (KCNA2) Polyclonal Antibody
Thermo Fisher Scientific의 KV1.2 (KCNA2) 폴리클로날 항체는 인간 및 마우스 반응성을 가지며, 웨스턴 블롯과 면역세포화학에 적합합니다. 항원 친화 크로마토그래피로 정제되었으며, 고순도(>95%)를 제공합니다. 연구용으로만 사용 가능합니다.
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- PA576901
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- pk
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Thermo Fisher Scientific KV1.2 (KCNA2) Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunocytochemistry (ICC/IF) | 1:50–1:100 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant full length Human KCNA2 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2720628 |
Product Specific Information
The antibody was affinity-purified from rabbit antiserum by affinity chromatography using epitope-specific immunogen. Purity is >95% (by SDS-PAGE).
Target Information
Kcna2 is a voltage-gated potassium channel (KV) that belongs to the 6-TM family of potassium channels, also comprising Ca2+-activated Slo (7-TM) and SK subfamilies. The alpha-subunits contain a single pore-forming region and combine to form tetramers.
Potassium channels regulate diverse physiological functions including neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. The Kcna2 gene encodes a member of the voltage-gated, shaker-related potassium channel subfamily, containing six membrane-spanning domains with a shaker-type repeat in the fourth segment. It belongs to the delayed rectifier class, enabling efficient neuronal repolarization after action potentials. The coding region of Kcna2 is intronless and clustered with KCNA3 and KCNA10 on chromosome 1.
Diseases associated with KCNA2 include Epileptic Encephalopathy (Early Infantile, 32) and Undetermined Early-Onset Epileptic Encephalopathy.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(이미지: PA5-76901_KV1.2_KCNA2_P16389-1_Rabbit.svg)
(이미지: PA5-76901_KV1.2_KCNA2_P16389-1_Rabbit_PDP.jpeg)
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