Thermo Fisher Scientific TOP2A Polyclonal Antibody
Human TOP2A 단백질을 인식하는 Rabbit Polyclonal Antibody로, WB, IHC, IP 등 다양한 실험에 사용 가능. Protein A로 정제된 액상 형태이며, 1 mg/mL 농도. 세포주기 분석 및 암 연구에 적합한 연구용 항체.
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Thermo Fisher Scientific TOP2A Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 5–10 µg/mL |
| Immunohistochemistry (IHC) | Assay-dependent |
| Immunoprecipitation (IP) | 10 µg/mL |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to aa 1513–1530 (RAKKPIKYLEESDEDDLF) from the C-terminus of human topoisomerase IIα |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS, pH 7.4, with 0.2% BSA |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_11000091 |
Product Specific Information
PA5-16322 targets Topoisomerase II alpha in IF, IHC, IP, and WB applications and shows reactivity with Human samples.
The immunogen is a synthetic peptide corresponding to aa 1513–1530 (RAKKPIKYLEESDEDDLF) from the C-terminus of human topoisomerase IIα.
Target Information
Topoisomerase IIα plays critical roles in DNA synthesis and transcription, as well as chromosomal segregation during mitosis.
It is a sensitive and specific marker of late S-, G2-, and M-phases in transformed and developmentally regulated normal cells.
Topo IIα is also implicated in drug resistance of tumor cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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