Thermo Fisher Scientific MiTF Recombinant Rabbit Monoclonal Antibody (6S9G4)
MiTF 단백질을 인식하는 Thermo Fisher Scientific의 재조합 토끼 단클론 항체. Western blot, ICC/IF, ELISA에 적합하며 높은 특이성과 재현성을 제공. 인간 및 랫트 시료에 반응하며 연구용으로만 사용 가능.
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Thermo Fisher Scientific MiTF Recombinant Rabbit Monoclonal Antibody (6S9G4)
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000–1:20,000 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| ELISA | 1 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Rat |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | 6S9G4 |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 402–526 of human MITF (NP_001341533.1) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.227 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 0.05% BSA, 50% glycerol |
| Contains | 0.05% ProClin 300 |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_3093734 |
Product Specific Information
Immunogen sequence:
HGLSLIPSTG LCSPDLVNRI IKQEPVLENC SQDLLQHHAD LTCTTTLDLT DGTITFNNNL GTGTEANQAY SVPTKMGSKL EDILMDDTLS PVGVTDPLLS SVSPGASKTS SRRSSMSMEE TEHTC
Target Information
Mi is a basic helix-loop-helix-leucine zipper (b-HLH-ZIP) transcription factor implicated in pigmentation, mast cells, and bone development.
Mutation of Mi causes Waardenburg Syndrome type II in humans. In mice, loss of pigmented cells in the skin, eye, and inner ear results, along with osteopetrosis and defects in natural killer and mast cells.
There are two known isoforms of Mi differing by 66 amino acids at the NH₂ terminus. Shorter forms are expressed in melanocytes and run as two bands at 52 kDa and 56 kDa, while the longer Mi form runs as a cluster of bands at 60–70 kDa in osteoclasts and in B16 melanoma cells, as well as mast cells and heart.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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