Thermo Fisher Scientific KCNK18 Polyclonal Antibody
Thermo Fisher Scientific의 KCNK18 폴리클로날 항체로, 인간, 생쥐, 랫드 반응성을 보이며 WB, IHC 등 다양한 응용에 적합합니다. 항원 친화 크로마토그래피로 정제된 액상 형태로 제공되며, 장기 보관 시 -20°C에서 안정적으로 유지됩니다.
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Applications
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:500–1:2,000 | View 1 publication |
| Immunohistochemistry (IHC) | – | View 1 publication |
| Immunohistochemistry (Paraffin) (IHC (P)) | Assay-dependent | – |
| Immunocytochemistry (ICC/IF) | Assay-dependent | – |
| Flow Cytometry (Flow) | Assay-dependent | – |
Product Specifications
| Specification | Details |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Published Species | Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide within mouse KCNK18 (aa 44–93) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 0.2% BSA, 50% glycerol |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2890459 |
Target Information
TRESK (TWIK-related spinal cord K⁺ channel) is a two-pore domain potassium channel that induces outward rectification and functions as a background K⁺ channel. It is abundantly expressed in the spinal cord, thymus, spleen, and leukemic T-lymphocytes.
TRESK is activated by increased cytoplasmic calcium concentration through calcineurin, as well as by acetylcholine and histamine.
It has been suggested that TRESK is linked to acute and chronic pain via calcineurin activation. Other studies indicate that TRESK may play a role in T-cell regulation and could be a potential target for treating T-cell–related immune dysfunction.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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