Thermo Fisher Scientific Phospho-EGFR (Tyr1068) Recombinant Rabbit Monoclonal Antibody (EGFRY1068-E5), PE

Thermo Fisher Scientific Phospho-EGFR (Tyr1068) Recombinant Rabbit Monoclonal Antibody (EGFRY1068-E5), PE

Applications

• Flow Cytometry (Flow)

Tested Dilution

• 5 µL / 1 × 10⁶ cells

Species Reactivity

• Human
• Mouse
• Rat

Product Specifications

Additional Formats

• Unconjugated
• APC
• FITC
• Custom conjugation available upon request

Product Specific Information

Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. Antibody DNA sequences from immunoreactive rabbits are cloned and screened to select optimal candidates.
Advantages include:

• Enhanced specificity and sensitivity
• Lot-to-lot consistency
• Animal origin-free formulation
• Broader immunoreactivity due to large rabbit immune repertoire

Target Information

EGFR (epidermal growth factor receptor) is a receptor tyrosine kinase activated by various growth factors. Overexpression is associated with multiple cancers.
EGFR gene is located on chromosome 7 and belongs to the HER/ERbB family (ERbB2, ERbB3, ERbB4).
Ligand binding (e.g., EGF, TGFα) induces receptor dimerization and autophosphorylation at tyrosine residues.
Overexpression observed in tumors of head and neck, brain, bladder, stomach, breast, lung, endometrium, cervix, vulva, ovary, esophagus, and squamous cell carcinoma.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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