Thermo Fisher Scientific PUF60 Polyclonal Antibody
Thermo Fisher Scientific의 PUF60 Polyclonal Antibody는 인간, 마우스, 랫트 시료에서 PUF60 단백질 검출용으로 최적화된 토끼 다클론 항체입니다. Western blot과 Immunoprecipitation에 적합하며, 고순도(>95%) 항원 친화 크로마토그래피로 정제되었습니다. 연구용으로만 사용 가능합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunoprecipitation (IP) | 1:20–1:50 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant full length Human PUF60 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2803987 |
Product Specific Information
Purity is >95% by SDS-PAGE.
Target Information
PUF60 encodes a Ro RNP-binding protein that interacts with Ro RNPs, potentially enhancing their function. It forms a ternary complex with the far upstream element (FUSE) and FUSE-binding protein, repressing c-myc reporter activity via FUSE. PUF60 also targets transcription factor IIH, inhibiting activated transcription. This gene is associated with xeroderma pigmentosum and has two alternatively spliced transcript variants encoding different isoforms, with evidence of multiple polyadenylation sites.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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