Thermo Fisher Scientific PPM1A Polyclonal Antibody
PPM1A 단백질 인산화효소를 인식하는 Rabbit Polyclonal 항체로, Western blot, IHC, ICC, ELISA에 사용 가능. Human, Mouse, Rat에 반응하며 항원 친화 크로마토그래피로 정제됨. 세포 스트레스 반응 및 종양 억제 연구에 적합.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100–1:500 |
| Immunocytochemistry (ICC/IF) | 1:100 |
| ELISA | 1:5,000–1:10,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH-conjugated synthetic peptide derived from human PP2CA/PPM1A (amino acids 101–200) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long-term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2803985 |
Product Specific Information
Purity is >95% by SDS-PAGE.
Target Information
PPM1A (Protein phosphatase 1A), also known as PPPM1A, belongs to the PP2C family. It is a serine/threonine protein phosphatase essential for regulating cellular stress responses in eukaryotes. PPM1A plays an important role in tumor suppression and negatively regulates several signaling pathways critical for trophoblast invasion. This protein is distributed in both the cytoplasm and nucleus of mammalian cells and has two isoforms produced by alternative splicing.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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