Thermo Fisher Scientific MAP2K2 Monoclonal Antibody (OTI5B4), TrueMAB
MAP2K2(MEK2) 단백질을 인식하는 Mouse monoclonal antibody로, WB와 ICC/IF에 적합합니다. Human, Mouse, Dog에 반응하며, Lyophilized 형태로 제공됩니다. 연구용으로 신호전달 경로 분석에 유용합니다.
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- CF505762
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Applications
Western Blot (WB)
- Tested Dilution: 1:200–1:2,000
Immunocytochemistry (ICC/IF)
- Tested Dilution: 1:100
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Dog, Human, Mouse |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI5B4 |
| Immunogen | Full length human recombinant protein of human MAP2K2 produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step (e.g., Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
MAP2K2 (MEK2) is a dual specificity serine/threonine kinase involved in mitogen growth factor signal transduction.
It belongs to a family of kinases that activate ERK1/2 and MAPK enzymes by phosphorylating residues within the TEY motif of the activation loop.
MEK1 and MEK2 are activated by dual phosphorylation on serine 218 and 222, while threonine 292 of MEK1 is phosphorylated by ERK2, forming a negative feedback loop that suppresses MEK1 activation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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