Thermo Fisher Scientific CD82 Polyclonal Antibody
Thermo Fisher Scientific의 CD82 Polyclonal Antibody는 인간 CD82/KAI-1 단백질을 인식하는 토끼 유래 항체입니다. WB, IHC, ELISA, IP에 적합하며, 단백질 A 및 항원 친화 크로마토그래피로 정제되었습니다. 보존제가 없으며 연구용으로만 사용됩니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:500–1:2,000 |
| ELISA | 1:5,000–1:10,000 |
| Immunoprecipitation (IP) | 1–4 µL/mg of lysate |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant Human CD82/KAI-1 protein (Gly111–Leu228) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A, Antigen affinity chromatography |
| Storage Buffer | PBS |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long term, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2787760 |
Product Specific Information
This product is preservative free. It is recommended to add sodium azide to avoid contamination (final concentration 0.05%–0.1%).
This antibody has specificity for Human CD82/KAI-1.
Target Information
The CD82 gene encodes a membrane glycoprotein that belongs to the transmembrane 4 superfamily. It functions as a metastasis suppressor and its expression is often downregulated during tumor progression. CD82 expression can be activated by p53 through a consensus binding sequence in its promoter region. Expression levels of CD82 and p53 are strongly correlated, and loss of both is associated with poor prognosis in prostate cancer. Two alternatively spliced transcript variants encoding distinct isoforms have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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