Thermo Fisher Scientific SLC12A2 (NKCC1) Polyclonal Antibody
SLC12A2(NKCC1) 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal 항체로, WB와 IHC에 적합합니다. 인간, 생쥐, 랫드 반응성이 있으며, 동결건조 형태로 제공됩니다. 세포 내 이온 균형 연구 및 막단백질 분석에 활용됩니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:300–1:2,000
Immunohistochemistry (IHC)
- Tested Dilution: 1:300–1:2,000
Miscellaneous PubMed (Misc)
- Publications: View 2 publications
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Published Species | Not Applicable |
| Host / Isotype | Rabbit / Ig |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide from the C-terminal region of human SLC12A2 conjugated to an immunogenic carrier protein |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | Not Determined |
| Storage Buffer | Whole serum |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Glycerol (1:1) may be added for added stability. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Reconstitute in 100 µL of sterile water. Centrifuge to remove any insoluble material.
- The peptide is homologous in rat and mouse.
- Specificity of this antibody: SLC12A2
Target Information
NKCC1 mediates sodium and chloride transport and reabsorption. It is a membrane protein important for maintaining proper ionic balance and cell volume.
NKCC1 operates as an electrically silent transporter system and is phosphorylated in response to DNA damage.
Three transcript variants encoding two different isoforms have been identified for NKCC1.
Diseases associated with SLC12A2 include Basosquamous Carcinoma and Metatypical Basal Cell Carcinoma.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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