Thermo Fisher Scientific DIS3 Polyclonal Antibody
DIS3 단백질을 인식하는 Thermo Fisher Scientific의 토끼 폴리클로날 항체. Western blot과 Immunoprecipitation에 적합하며, 1 mg/mL 농도의 액상 형태로 제공. 세포 내 RNA 처리 및 분해 연구에 유용. 연구용으로만 사용 가능.
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- A303766Ax (2개 옵션)
- 판매단위
- pk
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2개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific DIS3 Polyclonal Antibody
Applications
Western Blot (WB)
- Tested Dilution: 1:2,000–1:10,000
- References: -
Immunoprecipitation (IP)
- Tested Amount: 2–10 µg/mg lysate
- References: -
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 908 and 958 of human DIS3 mitotic control homolog |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
The recommended shelf life for this product is 1 year from the date of receipt.
Target Information
The exosome is involved in various cellular RNA processing and degradation events. DIS3, also known as exosome complex exonuclease RRP44, is a ribonuclease that directly participates in the processing, turnover, and surveillance of numerous RNA species. DIS3 localizes to both the cytoplasm and nucleus and contains one PINc domain. It is widely expressed, with the highest expression in testis, and is essential for processing 7S pre-RNA into a mature nuclear complex, ensuring proper mitotic progression. Abnormal DIS3 expression may be associated with colon cancer, implying a potential role in tumorigenesis.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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