Thermo Fisher Scientific CLDN7 Polyclonal Antibody
Human Claudin-7을 인식하는 Rabbit Polyclonal Antibody로 Western Blot 및 Immunoprecipitation에 사용 가능. 항원 친화 크로마토그래피로 정제된 액상 형태이며, 4°C에서 보관. 연구용으로만 사용.
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Thermo Fisher Scientific CLDN7 Polyclonal Antibody
Applications and Tested Dilution
- Western Blot (WB): 1:2,000–1:10,000
- Immunoprecipitation (IP): 20–40 µL/mg of lysate
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A region between residue 161 and 211 of human Claudin-7 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | Phosphate/tris citrate, pH 7.0–8.0 |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Predicted reactivity by homology: Rat, Mouse.
Target Information
This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets, and also play critical roles in maintaining cell polarity and signal transductions. Differential expression of this gene has been observed in various malignancies, including breast, ovarian, hepatocellular, urinary, prostate, lung, head and neck, and thyroid cancers. Alternatively spliced transcript variants encoding different isoforms have been found.
Usage Note
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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