Thermo Fisher Scientific TRPM2 Polyclonal Antibody
TRPM2 단백질을 인식하는 Goat Polyclonal 항체로, IHC, ICC, Flow Cytometry에 사용 가능. Human 시료에 반응하며, 0.5 mg/mL 농도의 액상 형태. 산화 스트레스 반응 연구 및 이온 채널 기능 분석에 적합.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | 3.75 µg/mL |
| Immunocytochemistry (ICC/IF) | 10 µg/mL |
| Flow Cytometry (Flow) | 10 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Peptide with sequence C-QQKQRPEQKIED |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Ammonium sulfate precipitation |
| Storage buffer | TBS, pH 7.3, with 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Wet ice |
| RRID | AB_2933044 |
Product Specific Information
This antibody is tested in Peptide ELISA with an antibody detection limit dilution of 1:16,000.
Target Information
TRPM2 belongs to the ion transport protein family, including Sodium, Potassium, and Calcium ion channels. These proteins possess six transmembrane helices, with the last two flanking a loop that determines ion selectivity.
TRPM2 is activated by oxidative stress and confers susceptibility to cell death. It functions as a calcium-permeable cation channel regulated by free intracellular ADP-ribose. Several alternatively spliced transcript variants of the TRPM2 gene have been described, though their full-length forms are not completely characterized.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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