Thermo Fisher Scientific Fibrinogen gamma Polyclonal Antibody
Human Fibrinogen gamma 단백질을 인식하는 Rabbit Polyclonal Antibody. Western blot, IHC, ICC 등 다양한 응용에 적합. 항원 친화 크로마토그래피로 정제된 고품질 항체. 4°C 단기 보관, -20°C 장기 보관 권장.
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Applications and Tested Dilutions
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:500–1:3,000 | - |
| Immunohistochemistry (Paraffin) (IHC-P) | 1:100–1:1,000 | - |
| Immunohistochemistry (Frozen) (IHC-F) | - | 1 publication |
| Immunocytochemistry (ICC/IF) | 1:100–1:1,000 | 1 publication |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Published Species | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein fragment corresponding to amino acids 194–368 of Human Fibrinogen gamma |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.39 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7, with 20% glycerol |
| Contains | 0.025% ProClin 300 |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2547208 |
Product Specific Information
- Recommended positive controls: 293T, A431, HeLa, HepG2, human plasma, HepG2 supernatant, Mouse plasma
- Predicted reactivity: Mouse (92%), Rat (91%), Pig (88%), Chicken (81%), Bovine (86%)
- Store product as a concentrated solution and centrifuge briefly prior to opening the vial.
Target Information
The Fibrinogen gamma gene encodes the gamma component of fibrinogen, a blood-borne glycoprotein composed of three pairs of nonidentical polypeptide chains. After vascular injury, fibrinogen is cleaved by thrombin to form fibrin, the main component of blood clots. Cleavage products of fibrinogen and fibrin also regulate cell adhesion, spreading, and display vasoconstrictor and chemotactic activities, acting as mitogens for several cell types. Mutations in this gene are associated with dysfibrinogenemia, hypofibrinogenemia, and thrombophilia. Alternative splicing results in two transcript variants encoding different isoforms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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