Thermo Fisher Scientific Kallikrein 11 Recombinant Rabbit Monoclonal Antibody (101)

Applications

• ELISA (ELISA): 1:250–1:2,000

Product Specifications

Product Specific Information

This product is preservative-free. It is recommended to add sodium azide to avoid contamination (final concentration 0.05%–0.1%).

Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The expression systems are developed by cloning specific antibody DNA sequences from immunoreactive rabbits. Individual clones are screened to select the best candidates for production.

Advantages of recombinant rabbit monoclonal antibodies:

• Better specificity and sensitivity
• Lot-to-lot consistency
• Animal origin-free formulations
• Broader immunoreactivity due to the larger rabbit immune repertoire

This antibody has specificity for Human KLK11/Kallikrein 11.

Target Information

Hippostasin, also known as KLK11, is a kallikrein-like serine protease with two alternatively spliced isoforms: brain-type and prostate-type. It plays roles in the prostate, including reproductive and tumorigenic functions. Elevated serum levels of KLK11 are found in 70% of women with ovarian cancer and 60% of men with prostate cancer. Analysis of the KLK11 biomarker in serum may aid in the diagnosis and monitoring of ovarian and prostatic carcinoma.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.