Thermo Fisher Scientific Actin, Muscle Specific (Muscle Cell Marker) Monoclonal Antibody (MSA/953)
근육 특이적 액틴 단백질을 인식하는 단일클론 항체로, 근육세포 마커 연구용에 적합. Western blot 및 면역조직화학(IHC) 분석에 사용 가능. 인간, 토끼, 쥐 시료 반응성. 단백질 A/G 정제 및 액상 형태로 제공. 연구용 한정 제품.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.5–1.0 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | Assay-dependent |
| Immunohistochemistry (PFA fixed) (IHC (PFA)) | 0.5–2 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Rabbit, Rat |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | MSA/953 |
| Immunogen | Synthetic peptide common among human muscle actins |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4, with 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | 4°C, do not freeze |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
The product encoded by this gene belongs to the actin family of proteins, which are highly conserved and play key roles in cell motility, structure, and integrity.
Alpha, beta, and gamma actin isoforms have been identified:
- Alpha actins: Major constituent of the contractile apparatus in muscle
- Beta and gamma actins: Involved in regulation of cell motility
This antibody targets alpha actin, found in skeletal muscle.
Mutations in this gene are associated with:
- Nemaline myopathy type 3
- Congenital myopathy with excess thin myofilaments
- Congenital myopathy with cores
- Congenital myopathy with fiber-type disproportion
These conditions are characterized by muscle fiber defects.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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