Thermo Fisher Scientific CD68 Monoclonal Antibody (FA-11), PE

Thermo Fisher Scientific CD68 Monoclonal Antibody (FA-11), PE

Applications

• Flow Cytometry (Flow)

Tested Dilution: Neat
Publications: -

Product Specifications

Additional Formats

• Biotin (MA5-16675)
• FITC (MA5-16676)
• Custom conjugation available upon request

Product Specific Information

• Membrane permeabilization is required for flow cytometry applications.
• For FACS analysis, use 10 µL of the suggested working dilution to label 1×10^6 cells in 100 µL.
• Reconstitute with 1 mL of distilled water. After reconstitution, store undiluted at 4°C in the dark.
• Rat anti-Mouse CD68 antibody (clone FA-11) recognizes mouse macrosialin, a heavily glycosylated transmembrane protein and murine homolog of human CD68.
• CD68 is classified as a scavenger receptor family member due to its LAMP-like domain.

Target Information

CD68 (Macrosialin) is a 110 kDa integral membrane glycoprotein predominantly expressed in lysosomes of monocytes and macrophages, and to a lesser extent in dendritic cells and granulocytes.
It plays a role in phagocytic activities and is expressed in various tissues and malignancies including AML and granulocytic sarcoma.
Elevated CD68 expression is observed in CD34+ cells in several human malignancies.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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