Thermo Fisher Scientific Oncostatin M Polyclonal Antibody
Human Oncostatin M에 특이적인 Rabbit Polyclonal Antibody로 Western Blot 및 ELISA에 적합. 보존제가 없는 액상 형태이며 Protein A로 정제. 단기 4°C, 장기 -20°C 보관 권장. 세포 성장 및 분화 연구에 활용 가능.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:1,000
ELISA
- Tested Dilution: 1:5,000–1:10,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant Human Oncostatin M/OSM protein (Met1–Arg221) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.16 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long term, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2788142 |
Product Specific Information
This product is preservative-free. It is recommended to add sodium azide to avoid contamination (final concentration 0.05%–0.1%).
This antibody has specificity for Human Oncostatin M/OSM.
Target Information
Oncostatin M (OSM) is a growth and differentiation factor involved in the regulation of neurogenesis, osteogenesis, and hematopoiesis.
Produced by activated T cells, monocytes, and Kaposi's sarcoma cells, OSM can exert both stimulatory and inhibitory effects on cell proliferation.
It stimulates proliferation of fibroblasts, smooth muscle cells, and Kaposi’s sarcoma cells, but inhibits growth of some normal and tumor cell lines.
OSM promotes cytokine release (e.g., IL-6, GM-CSF, G-CSF) from endothelial cells and enhances LDL receptor expression in hepatoma cells.
It shares structural and functional similarities with LIF, IL-6, and CNTF.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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