Thermo Fisher Scientific Phospho-ROCK2 (Tyr722) Polyclonal Antibody
ROCK2 단백질의 Tyr722 인산화 형태를 특이적으로 인식하는 rabbit polyclonal antibody. Western blot 및 IHC(P) 검증 완료. Human, Mouse, Rat 반응성. PBS/glycerol buffer에 보관되며 -20°C에서 안정적.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human ROCK2 (Accession O75116), corresponding to amino acid residues around phosphorylated Tyr722. |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Sequential chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2903031 |
Product Specific Information
This antibody detects endogenous levels of ROCK2 only when phosphorylated at Tyr722.
Target Information
ROCK2, the predominant ROCK isoform in skeletal muscle, is an important regulator downstream of Rho GTPases.
It regulates cytokinesis, smooth muscle contraction, formation of actin stress fibers and focal adhesions, and activation of the c-fos serum response element.
ROCK2, an isozyme of ROCK1, is a target for the small GTPase Rho.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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