Thermo Fisher Scientific CYP4Z1/CYP4Z2P Polyclonal Antibody
인간 CYP4Z1/CYP4Z2 단백질을 인식하는 Rabbit Polyclonal 항체입니다. Western blot과 IHC(Paraffin)에서 검증되었으며, 고순도의 affinity chromatography로 정제되었습니다. PBS/glycerol buffer에 보관되며 연구용으로 적합합니다.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000–1:3,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthesized peptide derived from human CYP4Z1/CYP4Z2 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2691468 |
Target Information
The cytochrome P450 (P450) superfamily of enzymes is one of three enzyme systems that metabolize the fatty acid arachidonic acid (AA) into regulators of vascular tone. P450 enzymes are monooxygenases requiring cofactors such as NADPH and P450 reductase. Over 200 genes encode P450s.
Epoxygenases convert AA to epoxyeicosatrienoic acids (EETs), while omega-hydroxylases produce 19- and 20-hydroxyeicosatetraenoic acids (HETEs).
In addition to fatty acid metabolism, P450s metabolize many drugs and toxins. Cytochrome P450 3A4 is highly expressed in the liver and small intestine and can be induced by barbiturates, glucocorticoids, and rifampicin.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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