Thermo Fisher Scientific IGFL2 Polyclonal Antibody
IGFL2 단백질을 인식하는 Thermo Fisher Scientific의 토끼 폴리클로날 항체로, Western blot에 최적화되어 있습니다. 인간 시료에 반응하며, 액상 형태로 제공되고 친화 크로마토그래피로 정제되었습니다. 연구용으로만 사용 가능합니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:1,000–1:3,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthesized peptide derived from human IGFL2 (amino acids 29–55) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2691464 |
Target Information
The insulin gene family, including insulin, relaxin, and insulin-like growth factors I and II (IGF-I and IGF-II), consists of structurally related polypeptides with divergent biological functions. IGF-I and IGF-II are critical regulators of cell proliferation and differentiation, mediating growth primarily through the IGF-I receptor (IGF-IR). IGF-I expression is regulated by growth hormone and supports postnatal growth, whereas IGF-II is induced by placental lactogen during prenatal development. IGF-II functions as a fetal growth factor and is abundantly expressed in placental trophoblasts. Variants in IGF-II and IGFBP1 genes are associated with metabolic changes induced by overfeeding. The human IGF-II gene is located on chromosome 11p15.5 and encodes a 180-amino-acid precursor protein.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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