Thermo Fisher Scientific GABRA4 Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

Assay-Dependent

-

Product Specifications

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Fusion protein from the cytoplasmic loop of the alpha 4 subunit

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.15 mg/mL

Storage conditions

-20°C

Shipping conditions

Wet ice

RRID

AB_2807456

Target Information

Gamma-aminobutyric acid is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. At least 16 distinct subunits of GABA-A receptors have been identified. This gene encodes subunit alpha-4, which is involved in the etiology of autism and eventually increases autism risk through interaction with another subunit, gamma-aminobutyric acid receptor beta-1. Alternatively spliced transcript variants encoding different isoforms have been found in this gene.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.