Thermo Fisher Scientific GABRA4 Polyclonal Antibody
Rabbit polyclonal antibody targeting GABRA4 alpha-4 subunit of GABA-A receptor. Suitable for Western blot applications. Supplied as an unconjugated liquid form with 0.15 mg/mL concentration. Stored at -20°C and shipped on wet ice for research use only.
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Thermo Fisher Scientific GABRA4 Polyclonal Antibody
Applications
- Western Blot (WB): Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Fusion protein from the cytoplasmic loop of the alpha 4 subunit |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.15 mg/mL |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2807456 |
Target Information
Gamma-aminobutyric acid (GABA) is the major inhibitory neurotransmitter in the mammalian brain, acting at GABA-A receptors which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor.
At least 16 distinct subunits of GABA-A receptors have been identified. The GABRA4 gene encodes the alpha-4 subunit, which has been implicated in the etiology of autism and may increase autism risk through interaction with another subunit, gamma-aminobutyric acid receptor beta-1.
Alternatively spliced transcript variants encoding different isoforms have been found in this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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