Thermo Fisher Scientific KCNN3 (KCa2.3, SK3) Polyclonal Antibody, Atto 594

Applications

• Immunohistochemistry (Frozen) (IHC (F))
  Tested Dilution: Assay-dependent

Product Specifications

Product Specific Information

• Reconstitution: Add 50 µL double distilled water (DDW), depending on sample size.
• Ships as lyophilized powder at room temperature; store at -20°C upon arrival.
• Reconstituted solution stable at 4°C for up to 1 week; for longer storage, aliquot and keep at -20°C.
• Avoid multiple freeze/thaw cycles.
• Centrifuge antibody preparations before use (10,000 × g, 5 min).

Target Information

Action potentials in vertebrate neurons are followed by an afterhyperpolarization (AHP) that can persist for several seconds, affecting neuronal firing patterns.
KCNN3, a member of the KCNN potassium channel family, encodes a voltage-independent calcium-activated channel contributing to the slow component of synaptic AHP.
The protein is an integral membrane component that forms a calcium-activated channel with calmodulin-binding subunits, regulating neuronal excitability.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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