Thermo Fisher Scientific KCNN3 (KCa2.3, SK3) Polyclonal Antibody, Atto 594
KCNN3(KCa2.3, SK3) 단백질을 표적하는 Atto 594 결합 폴리클로날 항체로, 인간·마우스·랫에서 반응합니다. 형광 이미징 및 IHC(F) 응용에 적합하며, 항원 친화 크로마토그래피로 정제되었습니다. 동결 건조 형태로 제공되며, -20°C 보관을 권장합니다.
- 카탈로그번호
- APC-025-AR-50UL
- 판매단위
- pk
카탈로그
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Applications
- Immunohistochemistry (Frozen) (IHC (F))
Tested Dilution: Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | DTSGHFHDSGVGDLDEDPKC (human KCNN3, aa 2–21, intracellular N-terminus) |
| Conjugate | Atto™ 594 |
| Excitation / Emission Max | 602 / 622 nm |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 1% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Reconstitution: Add 50 µL double distilled water (DDW), depending on sample size.
- Ships as lyophilized powder at room temperature; store at -20°C upon arrival.
- Reconstituted solution stable at 4°C for up to 1 week; for longer storage, aliquot and keep at -20°C.
- Avoid multiple freeze/thaw cycles.
- Centrifuge antibody preparations before use (10,000 × g, 5 min).
Target Information
Action potentials in vertebrate neurons are followed by an afterhyperpolarization (AHP) that can persist for several seconds, affecting neuronal firing patterns.
KCNN3, a member of the KCNN potassium channel family, encodes a voltage-independent calcium-activated channel contributing to the slow component of synaptic AHP.
The protein is an integral membrane component that forms a calcium-activated channel with calmodulin-binding subunits, regulating neuronal excitability.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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(해당 제품의 항원 구조 이미지 및 표적 단백질 관련 시각 자료)
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