Thermo Fisher Scientific PIWIL2 Polyclonal Antibody
Thermo Fisher Scientific의 PIWIL2 Polyclonal Antibody는 마우스 및 랫트 시료에 반응하며 Western blot과 ELISA에 적합합니다. Rabbit에서 유래한 IgG 항체로, 정제도 높고 안정적인 액상 형태로 제공됩니다. 생식세포 발달 연구 및 PIWI 단백질 계열 연구에 유용합니다.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000–1:3,000 |
| ELISA | 1 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 398–652 of mouse PIWIL2 (Q8CDG1) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 3.18 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | –20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2855585 |
Product Specific Information
Immunogen sequence:
QNKEHFQDEC SKLLVGSIVI TRYNNRTYRI DDVDWNKTPK DSFVMSDGKE ITFLEYYSKN YGITVKEDDQ PLLIHRPSER QNNHGMLLKG EILLLPELSF MTGIPEKMKK DFRAMKDLTQ QINLSPKQHH GALECLLQRI SQNETASNEL TRWGLSLHKD VHKIEGRLLP MERINLRNTS FVTSEDLNWV KEVTRDASIL TIPMHFWALF YPKRAMDQAR ELVNMLEKIA GPIGMRISPP AWVELKDDRI ETYIR
Target Information
The piwi gene of Drosophila belongs to a novel class of evolutionarily conserved genes (the piwi or Argonaute family). The Piwi family is required for germ and stem cell development in invertebrates. Two Piwi members, MIWI and MILI (Piwil2, Piwi-like protein 2), are essential for spermatogenesis in mouse.
MIWI and MILI partner with Piwi-interacting RNAs (piRNAs), which are 26–31 nucleotides in length, distinct from microRNAs (miRNAs) or short interfering RNAs (siRNAs).
MILI may be programmed by distinct piRNA populations at different stages of germ cell development, suggesting its important role in meiotic prophase progression.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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