Thermo Fisher Scientific Arginase 2 Monoclonal Antibody (GT11111)
Thermo Fisher Scientific의 Arginase 2 단클론 항체(GT11111)는 Human, Mouse, Rat에 반응하며 WB와 IHC(P)에 사용 가능. 단백질 G로 정제된 액상 항체로, 1 mg/mL 농도. Positive control은 mouse kidney이며, 연구용으로 적합.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:3,000
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:100–1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | GT11111 |
| Immunogen | Recombinant protein encompassing a sequence within the center region of human ARG2 (exact sequence proprietary) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein G |
| Storage Buffer | PBS |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2735112 |
Product Specific Information
- Positive Control: Mouse kidney
- Predicted Reactivity: Human (100%), Dog (85%), Rabbit (90%), Chicken (81%), Rhesus Monkey (99%), Bovine (93%)
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
Arginase catalyzes the hydrolysis of arginine to ornithine and urea. At least two isoforms of mammalian arginase exist (types I and II) which differ in tissue distribution, subcellular localization, immunologic cross-reactivity, and physiologic function.
The type II isoform encoded by this gene is located in the mitochondria and expressed in extra-hepatic tissues, especially kidney. Its physiologic role is not fully understood, but it is thought to play a role in nitric oxide and polyamine metabolism. Transcript variants resulting from alternative polyadenylation sites have been described.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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