Thermo Fisher Scientific IFNAR2 Recombinant Rabbit Monoclonal Antibody (123)

Applications

• Western Blot (WB): Tested dilution 1:500–1:2,000
• Publications: -

Product Specifications

Product Specific Information

This product is preservative free. It is recommended to add sodium azide to avoid contamination (final concentration 0.05%–0.1%).

Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The expression systems are developed by cloning the specific antibody DNA sequences from immunoreactive rabbits. Individual clones are screened to select the best candidates for production.

Advantages of recombinant rabbit monoclonal antibodies:

• Better specificity and sensitivity
• Lot-to-lot consistency
• Animal origin-free formulation
• Broader immunoreactivity due to large rabbit immune repertoire

This antibody has specificity for Human IFNAR2.

Target Information

Type I interferons (IFN-α and IFN-β) are structurally and functionally related proteins induced by viruses or double-stranded RNA, conferring an antiviral state in cells. IFN-α and IFN-β share a common cell surface receptor, while immune IFN (IFN-γ) binds to a distinct receptor.

The IFN-α/β receptor (IFNAR) is expressed as two alternatively spliced transcripts, IFNAR1 and IFNAR2, both involved in signal transduction and ligand binding.

For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.

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