Thermo Fisher Scientific Transferrin Receptor Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500

-

Product Specifications

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Synthetic peptide corresponding to residues D(152) D E E P P D A S L P P C(163) of the 20 kDa MMTV-R. if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:Transferrin Receptor (CD71),uniProtId:Q62351-1,ncbiNodeId:10090,antigenRange:152-163,antigenLength:763,antigenImageFileName:PA1-4111_Transferrin_Receptor_CD71_Q62351-1_Rabbit.svg,antigenImageFileNamePDP:PA1-4111_Transferrin_Receptor_CD71_Q62351-1_Rabbit_PDP.jpeg,sortOrder:3}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_559994

Product Specific Information

PA1-4111 detects mouse mammary tumor virus receptor in mouse samples.

PA1-4111 has been successfully used in Western blot procedures.

The PA1-4111 immunogen is a synthetic peptide corresponding to residues D(152) D E E P P D A S L P P C(163) of the 20 kDa MMTV-R.

Target Information

Cellular uptake of iron occurs via receptor-mediated endocytosis of ligand-occupied transferrin receptor into specialized endosomes. Endosomal acidification leads to iron release. The apotransferrin-receptor complex is then recycled to the cell surface with a return to neutral pH and the concomitant loss of affinity of apotransferrin for its receptor. Transferrin receptor is necessary for development of erythrocytes and the nervous system. Serum transferrin receptor (sTfR) is used as a means of detecting erythropoietin (EPO) misuse by athletes and as a diagnostic test for anemias resulting from a number of conditions including rheumatoid arthritis, pregnancy, irritable bowel syndrome and in HIV patients.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.