Thermo Fisher Scientific Transferrin Receptor Polyclonal Antibody
Transferrin receptor(CD71)을 인식하는 Rabbit Polyclonal Antibody로 Western blot에 적합. Mouse 시료에서 MMTV-R 검출에 사용. 합성 펩타이드(152-163aa)를 면역원으로 제작. 1 mg/mL 농도의 액상형 비접합 항체로 -20°C 보관.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to residues D(152) D E E P P D A S L P P C(163) of the 20 kDa MMTV-R |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_559994 |
Product Specific Information
- PA1-4111 detects mouse mammary tumor virus receptor in mouse samples.
- PA1-4111 has been successfully used in Western blot procedures.
- The immunogen is a synthetic peptide corresponding to residues D(152) D E E P P D A S L P P C(163) of the 20 kDa MMTV-R.
Target Information
Cellular uptake of iron occurs via receptor-mediated endocytosis of ligand-occupied transferrin receptor into specialized endosomes. Endosomal acidification leads to iron release. The apotransferrin-receptor complex is recycled to the cell surface, returning to neutral pH and losing affinity for its receptor.
Transferrin receptor is essential for erythrocyte and nervous system development. Serum transferrin receptor (sTfR) is used to detect erythropoietin (EPO) misuse and as a diagnostic marker for anemia related to conditions such as rheumatoid arthritis, pregnancy, irritable bowel syndrome, and HIV infection.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
- PA1-4111_Transferrin_Receptor_CD71_Q62351-1_Rabbit.svg
- PA1-4111_Transferrin_Receptor_CD71_Q62351-1_Rabbit_PDP.jpeg
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