Thermo Fisher Scientific Phospholamban Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:2,000

-

Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:200

-

Immunocytochemistry (ICC/IF)

1:50-1:100

-

Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Synthetic peptide within human Phospholamban aa 1-31 if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:Phospholamban,uniProtId:P26678-1,ncbiNodeId:9606,antigenRange:1-31,antigenLength:52,antigenImageFileName:PA5-119803_Phospholamban_P26678-1_Rabbit.svg,antigenImageFileNamePDP:PA5-119803_Phospholamban_P26678-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Affinity chromatography

Storage buffer

TBS, pH 7.4, with 50% glycerol, 0.2% BSA

Contains

0.05% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2913375

Product Specific Information

Positive Control: Rat heart tissue lysate, human heart tissue lysate, SH-SY5Y, rat heart tissue, human fetal skeletal muscle tissue, mouse heart tissue.

Subcellular Location: Endoplasmic reticulum membrane, Mitochondrion membrane, Sarcoplasmic reticulum membrane, Membrane.

Target Information

Phospholamban (PLB) is a 52 amino acid phosphoprotein which regulates the calcium pump of cardiac sarcoplasmic reticulum (SR). PLB is an oligomer of five identical subunits each having a cytoplasmic and transmembrane domain. The cytoplasmic domain (residues 1 to 25) contains the phosphorylation sites and is highly basic and readily cleaved by proteases whereas the transmembrane domain (residues 25 to 52) is mostly hydrophobic, protease resistant and stabilizes the pentamer.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.