Thermo Fisher Scientific MTNR1A Polyclonal Antibody
MTNR1A 단백질을 인식하는 Rabbit Polyclonal Antibody로, Human, Mouse, Rat 시료에 반응합니다. Western blot, IHC, ELISA에 적합하며, 고순도의 Affinity Chromatography로 정제되었습니다. 세포막 단백질 연구용으로 적합합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000–1:5,000 |
| Immunohistochemistry (Paraffin) (IHC-P) | 1:100–1:200 |
| ELISA | 1 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 281–350 of human MTNR1A (NP_005949.1) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 2.97 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.05% ProClin 300 |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2805229 |
Product Specific Information
- Immunogen sequence: YYMAYFNSCL NAIIYGLLNQ NFRKEYRRII VSLCTARVFF VDSSNDVADR VKWKPSPLMT NNNVVKVDSV
- Positive Samples: U-87MG, Mouse small intestine, Rat small intestine, Rat kidney
- Cellular Location: Cell membrane, Multi-pass membrane protein
Target Information
This gene encodes one of two high-affinity receptors for melatonin, the primary hormone secreted by the pineal gland. It is a G-protein coupled, 7-transmembrane receptor responsible for melatonin’s effects on mammalian circadian rhythm and reproductive alterations affected by day length. The receptor is an integral membrane protein localized to specific brain regions, including the hypothalamic suprachiasmatic nucleus (circadian rhythm) and the hypophysial pars tuberalis (reproductive effects).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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