Thermo Fisher Scientific pan AKT Polyclonal Antibody
Rabbit polyclonal antibody recognizing AKT1, AKT2, and AKT3. Suitable for WB and IHC in human, mouse, and rat samples. Lyophilized, unconjugated form with whole serum buffer. Stable at 4°C short term and -20°C long term. For research use only.
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Applications
Western Blot (WB)
- Tested Dilution: 1:300–1:2,000
- Publications: View 2 publications
Immunohistochemistry (IHC)
- Tested Dilution: 1:300–1:2,000
- Publications: View 2 publications
Miscellaneous PubMed (Misc)
- Publications: None
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Published Species | Not Applicable |
| Host / Isotype | Rabbit / Ig |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide from the C-terminal of mouse AKT1 (RAC-alpha serine/threonine-protein kinase, PKB, RAC) conjugated to an immunogenic carrier protein |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | Not Determined |
| Storage Buffer | Whole serum |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C avoiding freeze/thaw cycles. Glycerol (1:1) may be added for stability. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Reconstitute in 100 µL of sterile water. Centrifuge to remove any insoluble material.
- The antigen is homologous in rat, human, and chicken.
- Specificity: AKT1, AKT2, AKT3.
Target Information
AKT, also known as protein kinase B (PKB) or RAS-alpha, is a serine/threonine kinase involved in metabolic regulation, cell survival, and growth. It is activated by insulin, PI3K, IGF1, and other growth factors. AKT promotes cell survival by inhibiting apoptosis through phosphorylation and inactivation of targets such as forkhead transcription factors and caspase-9. The AKT pathway is a major focus in cancer drug discovery.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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