Thermo Fisher Scientific XRCC1 Monoclonal Antibody (33-2-5), Biotin

Applications

Tested Dilution

Publications

Western Blot (WB)

1-2 µg/mL

View 10 publications 10 publications

Immunohistochemistry (IHC)

-

View 2 publications 2 publications

Immunohistochemistry (Paraffin) (IHC (P))

1-2 µg/mL

-

Immunocytochemistry (ICC/IF)

-

View 4 publications 4 publications

Immunoprecipitation (IP)

2 µg/mL

-

Product Specifications

Species Reactivity

Human, Rat

Published species

Human, Rabbit

Host/Isotype

Mouse / IgG2b

Class

Monoclonal

Type

Antibody

Clone

33-2-5

Immunogen

Recombinant human XRCC1 protein

Conjugate

Biotin Biotin Biotin

View additional formats

• Unconjugated
• Request custom conjugation

Form

Liquid

Concentration

0.2 mg/mL

Purification

Protein A

Storage buffer

PBS, pH 7.4, with 0.2% BSA

Contains

0.09% sodium azide

Storage conditions

4° C

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_10979711

Product Specific Information

MA5-13409 targets XRCC1 in IHC (P), IP, and WB applications and shows reactivity with Human and Rat samples.

The MA5-13409 immunogen is recombinant human XRCC1 protein.

Target Information

XRCC1 (X-ray cross complementing factor-1) is involved in DNA base excision repair. XRCC1 is a 70 kDa protein that has been shown to be physically associated with other DNA repair enzymes, including poly (ADP-ribose) polymerase (PARP), DNA Ligase III and DNA polymerase beta. XRCC1 contains a BRCT domain (for BRCA1 carboxyl terminus) which was originally found in the tumor suppressor protein BRCA1. Recently, the BRCT domain has been shown to mediate the protein-protein interaction of XRCC1 and DNA ligase III-alpha.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.