Thermo Fisher Scientific Dystrophin Polyclonal Antibody
Rabbit polyclonal antibody targeting human Dystrophin protein. Validated for IHC (Paraffin) with dilution 1:1,000–1:2,500. Unconjugated, purified by antigen affinity chromatography. Supplied in PBS with glycerol and sodium azide. Suitable for research ...
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:1,000–1:2,500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human Dystrophin (control fragment: RP-92153) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.3 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term; for long-term storage, store at -20°C (avoid freeze/thaw cycles) |
| Shipping Conditions | Wet ice |
| RRID | AB_2856305 |
Product Specific Information
Immunogen sequence:
KQNDVHRAFK RELKTKEPVI MSTLETVRIF LTEQPLEGLE KLYQEPRELP PEERAQNVTR LLRKQAEEVN TEWEKLNLHS ADWQRKIDET LERLQELQEA TDELDLKLRQ AEVIKGSWQP VGDLLIDSLQ DHLEKVKALR GEIAPLKENV
Target Information
Dystrophin is a 427 kDa protein encoded by the DMB/BMD gene on the X chromosome (Xp21).
Western blotting and immunohistochemistry are established methods for detecting dystrophin abnormalities in muscle biopsies.
Such abnormalities are observed in nearly all patients with Duchenne or Becker muscular dystrophy (DMD/BMD), although genetic mutations may only be identified in approximately 65% of cases.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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