Thermo Fisher Scientific ARS2 Polyclonal Antibody
Human ARS2 단백질을 인식하는 Rabbit 폴리클로날 항체로, WB, IHC, ICC 등에 적합합니다. 고순도 항원 친화 크로마토그래피로 정제되었으며, 0.76 mg/mL 농도의 액상 형태입니다. 다양한 세포주에서 양성 대조군으로 사용 가능하며, 장기 보관 시 -20°C에서 안정적으로 유지됩니다.
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- PA531593
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Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:1,000–1:20,000 | View 1 publication |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100–1:1,000 | - |
| Immunocytochemistry (ICC/IF) | 1:100–1:1,000 | - |
| Miscellaneous PubMed (Misc) | - | View 1 publication |
Product Specifications
| Item | Description |
|---|---|
| Species Reactivity | Human |
| Published Species | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein fragment corresponding to amino acids 3–189 of Human ARS2 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.76 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | 0.1M Tris glycine, pH 7, with 20% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2549066 |
Product Specific Information
- Recommended positive controls: 293T, A431, Jurkat, Raji, HeLa, HepG2
- Predicted reactivity: Mouse (97%), Zebrafish (80%), Bovine (97%)
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
Acts as a mediator between the cap-binding complex (CBC) and the primary microRNAs (miRNAs) processing machinery during cell proliferation. Contributes to the stability and delivery of capped primary miRNA transcripts to the processing complex containing DGCR8 and DROSHA, playing a role in RNA-mediated gene silencing (RNAi). Binds capped RNAs via interaction with NCBP1/CBP80 of the CBC complex. Involved in S phase cell cycle progression. Modulates arsenic sensitivity rather than conferring resistance. Independently promotes neural stem cell self-renewal by binding the SOX2 promoter and activating its transcription. [UniProt]
⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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