Thermo Fisher Scientific BAG1 Polyclonal Antibody
Human BAG1 단백질에 특이적인 Rabbit Polyclonal Antibody로, IHC(P)에서 1:50~1:200 희석 비율로 사용 가능. 항원 친화 크로마토그래피로 정제되었으며 PBS/glycerol buffer에 보관. BCL2 관련 항아포토시스 경로 연구용으로 적합.
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:50–1:200
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant Protein corresponding to Human BAG1 (Recombinant protein control fragment Product #RP-90895) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2856243 |
Product Specific Information
Immunogen sequence:
GKSLKEMETP LSALGIQDGC RVMLIGKKNS PQEEVELKKL KHLEKSVEKI ADQLEELNKE LTGIQQGFLP KDLQAEALCK LDRRVKATIE QFMKILEEID TLILPENFKD SRLKRKGLVK KVQAFLAECD TVEQNICQET E
Target Information
The oncogene BCL2 is a membrane protein that blocks a step in a pathway leading to apoptosis or programmed cell death.
The protein encoded by this gene binds to BCL2 and is referred to as BCL2-associated athanogene (BAG1).
It enhances the anti-apoptotic effects of BCL2 and represents a link between growth factor receptors and anti-apoptotic mechanisms.
At least three protein isoforms are encoded by this mRNA through the use of a non-AUG (CUG) start site and alternative downstream AUG translation initiation sites.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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